The development of catalytic oxovanadiumivcontaining microspheres for the oxidation. Oxovanadium complexes were screened for the oxidation of benzoin to benzil using h 2 o 2 as oxidant. The limits of practical utilization of these reagents involves the use of stoichiometric amounts of corrosive acids or. Synthesis, characterization and biological properties of. Ferreira c,d, margarida godinho c, paula ferreira e, a department of chemistry and biochemistry, cqb, faculty. The oxovanadiumiv complexes exhibit an intense band at 980981 cm1, which has been assigned to the vo stretching frequency 12. Oxovanadium complexes in bio medical applications bjstr. Insitu preparation of oxovanadium iv complexes with ligands derived by condensation of furil with 1,4diaminobenzene or 3,4diaminopyridine. Photocytotoxic oxovanadiumiv complexes showing light.
Synthesis of oxovanadium iv complexes with tetraaza. The complexes are soluble in dmf and dmso but insoluble in organic solvents like methanol, ethanol and acetone. Oxovanadiumiv complexes containing bidentate schiffbase. Apr 12, 2018 leishmaniasis is an endemic disease affecting a diverse spectra of populations, with 1. The complexes of ebcp and pbcp, 10 and 11, did not give positive test for so ion and the molar. Pdf synthesis, molecular structure and properties of oxo. These were synthesised in aqueous solution by removing the chloride ligand from complexes 2 and 4 using agpf6 to give the aqua complex. The third vanadium binds to phenolic and keto oxygen atoms on rings b and c to form complex 1. The magnetic data for 1 and 2 are well described by the curieweiss law with c0. Oxygen atom exchange reaction between tetradentate schiff. New series of oxovanadiumiv complexes isolated from 2,4,6tris2pyridyl1,3,5triazine l1 are incorporated and portrayed using spectroscopic ir, uvvis, esr, mass spectrometric, magnetic moment, thermal and cyclic voltammetry measurements.
Oxovanadium complexes in catalytic oxidations sciencedirect. They have been made from several 5substituted jv2hydroxyphenylsalicylideneieanes and have been oxovanadiumiv complexes 301 studied27 magnetically between 1. The interaction of these complexes with calfthymus dna ctdna was investigated using. Three vanadyl complexes of bidentate schiff bases from vanillin with anthranilic acid va, 4aminoantipyrine with vanillin 4av as well as 4aminoantipyrine with furfural 4af have been synthesized and characterized using elemental analysis, ftir, uvvis, esr spectroscopic methods, magnetic susceptibility, molar conductivity measurements and thermal analysis. Iceren sekiz oksovanadyumiv kompleksi uzerine teorik cal. Synthesis and crystal structure of an oxovanadium iv complex. Synthesis, molecular structure and properties of oxovanadiumiv complexes containing the oxydiacetate ligand. Oxidation of benzoin catalyzed by oxovanadiumiv schiff base. The complexes show poor chemical nuclease activity in dark in the presence of 3mercaptopropionic acid or hydrogen peroxide.
Thermal dehydrogenation of oxovanadiumiv complexes with. The infrared spectra of the complexes in the range 4000200 cm1, were recorded in potassium bromide medium on perkinelmer 621 and beckmann acculab9 spectrophotometers. Interaction of oxovanadiumivsalphen complexes with bovine serum albumin and their cytotoxicity against cancer. Keywords oxovanadium iv complexes, antimicrobial activity, cytotoxic activity, breast cancer 1. Chemical composition of 11 oxovanadiumiv vo complexes. The synthesised oxovanadiumiv complexes were characterized by elemental analysis, electrical conductance, magnetic moment measurements and spectral infrared, electronic and electron spin resonance data. Theoretical studies on eight oxovanadiumiv complexes.
New series of oxovanadium iv complexes isolated from 2,4,6tris2pyridyl1,3,5triazine l1 are incorporated and portrayed using spectroscopic ir, uvvis, esr, mass spectrometric, magnetic moment, thermal and cyclic voltammetry measurements. Synthesis of oxovanadium iv schiff base complexes derived from. Oxovanadium complexes are known as potential inhibitors of different enzymes. The photocytotoxicity of complex 3 has been studied using. Preparation and structural characterization of oxovanadiumv complexes with schiff bases and their inhibition studies on helicobacter pylori urease. Photocleavage properties and dnabinding studies of. Pdf bactericidal activity of different oxovanadiumiv complexes.
The complexes were characterized by elemental analyses, molar conductance, magnetic moments, and. Synthesis, crystal structure, thermal stability, and magnetic properties of the new oxovanadiumiv complexes vo 2 l 2 oet 2 with mixed diketonato l acac c 5 h 7 o 2. Apr 01, 2009 read oxovanadiumiv complexes of carbohydrates. Complex 2 showed greater antitumor efficiency than that of complex 1. Structure and reactivity as multielectron redox catalysts. Synthesis, characterisation and antibacterial studies of. The conventional oxidizing agents yielded mainly benzaldehyde orand benzoic acid and only a trace amount of benzil. The present paper reports the synthesis and characterization of some new sulfa drug based schiff base oxovanadiumiv complexes of composition. This confirms the presence of a single vanadium iv cation, hence. May 30, 2000 read oxovanadium iv and oxovanadium v complexes relevant to biological systems, journal of inorganic biochemistry on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Oxovanadiumiv complexes of bioinorganic and medicinal relevance.
These complexes have been screened for their antibacterial activity against organisms like e. The synthesis and properties of some oxovanadiumiv complexes, vol 2, containing nsubstituted salicylaldimines l are reported. Synthesis and characterization of oxovanadiumiv macrocyclic. Oxovanadiumiv complexes of curcumin for cellular imaging and mitochondria targeted photocytotoxicity article pdf available in dalton transactions 4335 july 2014 with 1,204 reads.
New series of oxovanadium iv complexes isolated from 2,4,6tris2pyridyl1,3,5triazine l 1 are incorporated and portrayed using spectroscopic ir, uvvis, esr, mass spectrometric, magnetic moment, thermal and cyclic voltammetry measurements. Moreover, they show chelating properties towards vanadyl cation that could be used in insulinmimetic compound development. Magnetic properties of oxovanadiumiv complexes op substituted n hydroxyalkyl salicylideneimines thesis presented to the graduate council of the north texas state university in partial fulfillment of the requirements for the degree of master of science by elbert franklin carey, jr. Oxovanadium and oxomolybdenum clusters and solids incorporating oxygen. Oxovanadiumiiiv mononuclear complexes and their linear. The prepared macrocyclic complexes were characterized by elemental analyses, molar conductance, magnetic moments, and. Molecules free fulltext oxovanadiumiv coordination. Introduction the development of transition metal complexes which are actually to be utilized in a wide range of biochemistry and medicine as well as therapeutic medication against tumor cells has achieved fantastic step forward in. Synthesis and structural studies of oxovanadium iv complexes author. In an effort to study the spectral, magnetic, and stereochemical properties of vanadyl complexes, both a new series of vanadyl complexes derived from type vii ligands with subnormal magnetic moment and from type viii ligands with normal magnetic moment are synthesized and characterized.
Oxovanadium complexes have a variety of application in biological, clinical and analytical fields. Oxovanadium complexes in bio medical applications request pdf. Ishaque khan department of chemical and biological sciences, illinois institute of technology, chicago, il. Oxovanadiumiv complexes containing 1,10phenanthroline, 2,2. Free fulltext pdf articles from hundreds of disciplines, all in one place oxidation of benzoin catalyzed by oxovanadium iv schiff base complexes pdf paperity toggle navigation. Oxovanadiumiv complexes of bioinorganic and medicinal.
Interaction of oxovanadiumivsalphen complexes with bovine. Complexes of 4apy and an did not react with orthophenanthroline ophen and dipyridyl dipy. The structure determinations of vo 2 acac 2 oet 2 p2 1 c, with a 14. Synthesis, structure and spectroscopic properties of.
The complexes are analyzed for carbon, hydrogen, nitrogen, sulphur. Feb 01, 2010 metal complexes of cyclam and bicyclam in solution give rise to several different configurational isomers, each dependent on the chirality of the 4 ring nitrogens. Synthesis and spectral studies of some oxovanadiumiv and. The complex of 5chlorooxine is very unstable and oxidizes rapidly, generating a vv complex of stoichiometry voqcl2oh which could also be prepared in pure form. Synthesis and characterization of some novel schiff base. New squarepyramidal oxovanadium iv complexes derived from. An unusually low v o stretching frequency pdf available in dalton transactions 4335 july 2014 with 1,204 reads. The ir spectra of the oxovanadiumiv complexes shows that, the ligands behave in a tridentate way. Oxovanadium forms 5coordinate complexes in all the three complexes. Oxidation of benzoin catalyzed by oxovanadium iv schiff. The colour of these complexes vary from green to snuff. New therapeutic options that have been previously identified, but still underappreciated as potential pharmaceutical targets, are leishmania secreted acid phosphatases sap. Preparation and structural characterization of oxovanadium.
The syntheses of new oxovanadiumiv complexes having general formula vomacso 4 have been carried out by using in situ method of preparation where vanadyl ion acts as kinetic template for the ligands derived by condensation of 2,2. All the vanadyl complexes are crystalline, nonhygroscopic, and stable at room temperature. Oxovanadiumiv complexes of the type vomacso 4 where mac tetraaza macrocyclic ligands derived by condensation of thenil with 1,4diaminobenzene or 3,4diaminopyridine and their reaction with. Two oxovanadiumiv complexes of vomsatscphen, 1 msatsc.
Magnetic exchange in oxovanadiumiv complexes with nsalicxlidsnbamino acids dissertation presented to the graduate council of the north texas state university in partial fulfillment of the requirements for the degree of doctor of philosophy by james hungjen hu, b. Synthesis and characterization of oxovanadiumiv complexes. Oxovanadiumiv complexes of the type vomacso4 where mac tetraaza macrocyclic ligands derived by condensation of thenil with 1. This is in contrast to the structures of oxovanadium iv salen complexes, in which the nitrogen atoms are forced to coordinate cis to the vanadium center. The complexes 1, 2, and 4 were more effective than metronidazole, a commonly used drug against amoebiasis, suggesting that oxovanadium v complexes derived from thiohydrazones may open a new. The oxovanadiumiv complexes have been synthesized and characterized by elemental analysis, ftir spectroscopy, uvvis spectroscopy, epr and xray diffraction xrd. The structures of compounds i and ii are solved by direct methods and refined to r 1 0. Jan 07, 20 oxovanadium complexes were screened for the oxidation of benzoin to benzil using h 2 o 2 as oxidant. Pdf oxovanadiumiv complexes have been synthesized and characterized the general composition vola, where h2l salicylideneoaminothiophenol. Oxovanadiumiv complexes with onnotype tetradentate schiff base ligands.
The structure of complex 4 can be described as a square planar pyramid. Synthesis and structure of oxovanadiumiv complexes vo. Theoretical studies on eight oxovanadiumiv complexes with salicylaldehyde and aniline ligands salisilaldehid ve anilin ligandlar. Frontiers evidence that speciation of oxovanadium complexes. The structures of vo3etosalmesostien and vo3etosalton were determined by xray structure analyses. Oxovanadiumiv complexes of halogenated oxines springerlink. Synthesis and characterization of nonoxovanadiumiv. Oxovanadium iv and oxovanadium v complexes with the stoichiometries vonoq2 and vonoq2oh respectively, containing the noxide of 8hydroxyquinoline noqh as a ligand were synthesized and. Jones lawrence livermore national laboratory, university of california, livermore, ca 94550, u. The catalytic activity results demonstrate that these catalytic systems are both highly active and selective for the oxidation of benzoin under mild reaction. A further examination of the ir spectra of the complexes reveals a band in the 980 and 981 cm1 region. Synthesis and catalytic properties of manganeseii and oxovanadiumiv complexes anchored to mesoporous mcm41 tiago a.
The room temperature xband epr spectra exhibit eight lines due to hyperfine splitting of 51v, whose nuclear spin number i 72. T1 magnetic properties of polynuclear oxovanadiumiv complexes with tetradentate schiff base ligands. Oxovanadiumiv complexes with onno chelating ligands as catalysts for ethylene homo and copolymerization by marzena bialek, anna leksza, anna piechota, krzysztof kurzak and katarzyna koprek download pdf 866 kb. The oxovanadium iv complexes of the type vomac so 4 are synthesized with tetraaza ligands derived from condensation of thenil with 1,2diaminopropane or 1,4diaminobutane in 1. This article is from chemistry central journal, volume 7. These complexes have a distorted octahedral geometry and yield v2o5 as a stable residue during thermal decomposition in static air atmosphere with loss of h2o molecule in the first step. Effect of oxovanadiumiv complexes on nondiabetic and streptozotocindiabetic rats. Introduction vanadium complexes have various biological activities, for example, an insulinlike activity 12 and the decorresponding author. Oxovanadiumiv complexes of substituted n2thiophenyl. The complexes have been characterized by elemental analyses, molar conductance measurements, molecular weight determinations and infrared, electronic and fabms spectral and magnetic moment studies. Redox interconversion of non oxido vanadium complexes accompanied by acidbase.
The nitrogen atoms in the pyridine rings of the ligands are positioned trans to each other. Anabothlavenkata kantha rao, suresh bhagwanji rewatkar subject. Research article open access oxidation of benzoin catalyzed. Synthesis and in vitro antitumor activity of two mixedligand. Oxovanadium iiiv mononuclear complexes and their linear assemblies bearing tetradentate schiff base ligands. The experimental data for 1, 2 and 3, plotted as the thermal variations of reciprocal molar susceptibility. Ferroelectric and mesomorphic properties of oxovanadiumiv. Active and selective catalytic systems of new unsymmetrical oxovanadiumiv schiff base complexes for the oxidation of benzoin is reported.
Oxovanadium complexes, synthesis, dnabinding, photocleavage 1. The oxidative transformation of benzoin to benzil has been accomplished by the use. Oxovanadiumiv complexes with onnochelating ligands as. In this work, the formation of coordination compounds of oxovanadium iv with four kojic acid 5hydroxy2hydroxymethyl4pyrone derivatives was studied. Synthesis and catalytic properties of manganeseii and. The room temperature magnetic moments of the complexes lying in the range 1. The names of the 11 oxovanadium complexes synthesized and tested in this study are listed in table 1. Oxidation of benzoin catalyzed by oxovanadiumiv schiff. Synthesis, structure and reactivity of oxovanadiumiv. It is concluded from the result, all the oxovanadiumiv complexes are 1.
The dpq and dppz complexes are efficient photocleavers of plasmid dna in uva light of 365 nm via a mechanistic pathway that involves formation of both singlet oxygen and hydroxyl radicals. The effect of time, solvent and temperature were optimized to obtain maximum yield. Oxidation of benzoin catalyzed by oxovanadium iv schiff base complexes chemistry central journal, dec 20 tahseen a alsalim, jabbar s hadi, omar n ali, hanna s abbo, salam jj titinchi. The oxygen atom exchange reaction between the terminal oxygen atom vo of tetradentate schiff baseoxovanadiumiv complexes and water slowly proceeds in dmso solutions. Synthesis of oxovanadiumiv complexes with tetraaza.
The infrared spectra of all complexes have been recorded and are discussed in detail. The spectral data of the complexes indicate that ligands act as tetradentate chelating agent and complexes are five coordinate. Synthesis, characterization and 3d molecular modeling and analysis of some oxovanadiumiv complexes involving the o, ndonor environment of pyrazolonebased sulfa drug schiff bases. Molar conductance data of oxovanadiumiv complexes complexes solvent molar conductance m. These coordination complexes are stabilized with 5membered mono or bisphenanthroline, bipyridyl, and acetophenonetype bidentate ligands with the vanadium atom. Increased importance of oxovanadium complexes are due to its significance in biological systems and affinity towards the donor ligands. The synthesised oxovanadium iv complexes were characterized by elemental analysis, electrical conductance, magnetic moment measurements and spectral infrared, electronic and electron spin resonance data.
Free fulltext pdf articles from hundreds of disciplines, all in one place oxovanadiumiv complexes with onno chelating ligands as catalysts for ethylene homo and copolymerization pdf paperity toggle navigation. New squarepyramidal oxovanadium iv complexes derived. A brief overview, journal of inorganic biochemistry on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The complexes 1, 2, and 4 were more effective than metronidazole, a commonly used drug against amoebiasis, suggesting that oxovanadiumv complexes derived from thiohydrazones may open a new. The catalytic activity of oxovanadium complexes for the oxidation of benzoin to benzil has been studied and the effect of time, solvent and temperature were optimized to produce maximum yield. The structures of the new complexes were validated by elemental analysis c, h, n and ftir spectroscopy. Introduction the development of transition metal complexes which are actually to be utilized in a wide range of biochemistry and medicine as well as therapeutic medication against tumor cells has achieved fantastic step forward in past decades. Nonoxovanadiumiv and oxovanadiumv complexes with mixed. This contribution is an overview on recent advances since 2000 on the application of oxovanadium complexes as catalysts or mediators for oxidations by molecular oxygen, peroxidative oxygenations both including epoxidations, halogenations and carboxylations of aliphatic and aromatic hydrocarbons, andor olefins, toward the syntheses of a variety of organic compounds, such as alcohols. Magnetic properties of polynuclear oxovanadiumiv complexes.
The chiral and racemic oxovanadium iv salmmen complexes voxc16salmmen x r, s and rac were synthesized. The oxidative transformation of benzoin to benzil has been accomplished by the use of a wide variety of reagents or catalysts and different reaction procedures. The outcomes propose that l1 coordinates in different ways in all complexes through one nitrogen of triazine and nitrogen atoms of pyridine. The results demonstrate that l 1 acts in various styles of chelation with v 3 o 3 l 1so 4 3 etoh 12 h 2 o 32 1, vol 12,4. All complexes exhibited both smectic a and chiral smectic c mesophases above 360 k, and ferroelectric property was observed even for racemic compound. Oxidation did not proceed when the reaction was carried out in the presence of either hydrogen peroxide or oxovanadium complexes only.
Pdf oxovanadiumiv complexes of curcumin for cellular. The oxovanadium complexes synthesized are investigated by vibrational spectroscopy. The oxovanadium complexes have a square pyramidal geometry with the oxo ligand o 2. Five complexes were prepared containing voso 4 and the ligands 4aminopyridine 4apy, 3aminopyridine 3apy, 2aminopyridine 2apy, 2aminopyrimidine 2apym, and aniline an. Current treatment options are costly and have harsh side effects. Hydroxypyrone derivatives have a good bioavailability in rats and mice and have been used in drug development. In recent years, vanadium complexes have attracted much attention for their potential utility as catalysts for various types of reactions. Spermicidal activity of oxovanadiumiv complexes of 1,10. Application of oxovanadium complex stabilized by n,n,n,n. Pdf effect of oxovanadiumiv complexes on nondiabetic. The complexes 79 analyzed for cl and s and the molar conductance was found between 46 and 51 ohmi cm2 morl, indicating them 1. A series of oxovanadiumiv complexes of the type vomacso 4 where mac tetraazamacrocyclic ligands derived from condensation of 4,4,4trifluro12furyl1,3butanedione or 4,4,4trifluro12thenyl1,3butanedione with pphenylenediamine and their reaction with. Oxovanadium complexes with schiff based ligands have wild application in catalysis, antibacterial properties, medicine and antioxidative properties 1,2.
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